Tm

Species Rattus norvegicus
Alternate Name(s) tremor
Description tremor
Chromosome 10
Locus 10
Reference(s) Akimitsu T, Kurisu K, Hanaya R, Iida K, Kiura Y, Arita K, Matsubayashi H, Ishihara K, Kitada K, Serikawa T, Sasa M. Epileptic seizures induced by N-acetyl-L-aspartate in rats: in vivo and in vitro studies. Brain Res 2000 Apr 7;861(1):143-50.

Amano T, Aihua Z, Matsubayashi H, Seki T, Serikawa T, Sasa M, Sakai N. Antiepileptic Effects of Single and Repeated Oral Administrations of S-312-d, a Novel Calcium Channel Antagonist, on Tonic Convulsions in Spontaneously Epileptic Rats. J Pharmacol Sci. 2004 Jul;95(3):355-62.

Amano T, Matsubayashi H, Ozkan ED, Sasa M, Serikawa T, Ueda T. Aberrant reduction of an inhibitory protein factor in a rat epileptic model. Epilepsy Res 2002 Sep;51(1-2):81-91.

Kitada K, Akimitsu T, Shigematsu Y, Kondo A, Maihara T, Yokoi N, Kuramoto T, Sasa M, Serikawa T. Accumulation of N-acetyl-L-aspartate in the brain of the tremor rat, a mutant exhibiting absence-like seizure and spongiform degeneration in the central nervous system. J Neurochem 2000 Jun;74(6):2512-9.

Kuramoto, T, Mori, M, Yamada, J and Serikawa, T. Tremor and zitter, causative mutant genes for epilepsy with spongiform encephalopathy in spontaneously epileptic rat (ser), are tightly linked to synaptobrevin-2 and prion proteins, respectively. Biochemical and Biophysical Research Communication, 200:1161-1168, 1994.

Maihara T, Noda A, Yamazoe H, Voigt B, Kitada K, Serikawa T. Chromosomal mapping of genes for epilepsy in NER: a rat strain with tonic-clonic seizures. Epilepsia 2000 Aug;41(8):941-9.

Noda A, Hashizume R, Maihara T, Tomizawa Y, Ito Y, Inoue M, Kobayashi K, Asano Y, Sasa M, Serikawa T. NER rat strain: a new type of genetic model in epilepsy research. Epilepsia 1998 Jan;39(1):99-107.

Seki T, Matsubayashi H, Amano T, Kitada K, Serikawa T, Sakai N, Sasa M. Adenoviral gene transfer of aspartoacylase into the tremor rat, a genetic model of epilepsy, as a trial of gene therapy for inherited epileptic disorder. Neurosci Lett 2002 Aug 16;328(3):249-52.

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