Kcna1

Species Mus musculus
Alternate Name(s) MBK1, Mk-1, Shak, Kv1.1, Kca1-1, mceph
Description potassium voltage-gated channel, shaker-related subfamily, member 1
Chromosome 6
Locus 6 61.0 cM
Human Homolog KCNA1
Protein Alignment Homo sapiens:

Mus musculus:
Reference(s) Li X, Kuang H, Jiang N, Hu Y. Involvement of Scn1b and Kcna1 ion channels in audiogenic seizures and PTZ-induced epilepsy. Epilepsy Res. 2005 Sep 9; [Epub ahead of print].

Lopantsev V, Tempel BL, Schwartzkroin PA. Hyperexcitability of CA3 Pyramidal Cells in Mice Lacking the Potassium Channel Subunit Kv1.1. Epilepsia. 2003 Dec;44(12):1506-12.

Smart SL, Lopantsev V, Zhang CL, Robbins CA, Wang H, Chiu SY, Schwartzkroin PA, Messing A, Tempel BL. Deletion of the K(V)1.1 potassium channel causes epilepsy in mice. Neuron. 1998 Apr;20(4):809-19.

Petersson S, Persson AS, Johansen JE, Ingvar M, Nilsson J, Klement G, Arhem P, Schalling M, Lavebratt C. Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly. Eur J Neurosci. 2003 Dec;18(12):3231-3240.

van Brederode JF, Rho JM, Cerne R, Tempel BL, Spain WJ. Evidence of altered inhibition in layer V pyramidal neurons from neocortex of Kcna1-null mice. Neuroscience. 2001;103(4):921-9.

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