| Species |
Mus musculus |
| Alternate Name(s) |
jerky |
| Description |
jerky
|
| Chromosome |
15
|
| Locus |
15 42.8 cM |
| Protein Alignment |
Homo sapiens:
Mus musculus:
 |
| Reference(s) |
Donovan GP, Harden C, Gal J, Ho L, Sibille E, Trifiletti R, Gudas LJ, Toth M. Sensitivity to jerky gene dosage underlies epileptic seizures in mice. J Neurosci. 1997 Jun 15;17(12):4562-9.
Liu W, Seto J, Donovan G, Toth M. Jerky, a protein deficient in a mouse epilepsy model, is associated with translationally inactive mRNA in neurons. J Neurosci. 2002 Jan 1;22(1):176-82.
Liu W, Seto J, Sibille E, Toth M. The RNA binding domain of Jerky consists of tandemly arranged helix-turn-helix/homeodomain-like motifs and binds specific sets of mRNAs. Mol Cell Biol. 2003 Jun;23(12):4083-93.
Moore T, Hecquet S, McLellann A, Ville D, Grid D, Picard F, Moulard B, Asherson P, Makoff AJ, McCormick D, Nashef L, Froguel P, Arzimanoglou A, LeGuern E, Bailleul B. Polymorphism analysis of JRK/JH8, the human homologue of mouse jerky, and description of a rare mutation in a case of CAE evolving to JME. Epilepsy Res. 2001 Aug;46(2):157-67.
Toth M. RNA binding proteins in epilepsy. Gene Function & Disease 2001, Volume 2, Issue 2-3, pp. 95-98.
Toth M, Grimsby J, Buzsaki G, Donovan GP. Epileptic seizures caused by inactivation of a novel gene, jerky, related to centromere binding protein-B in transgenic mice. Nat Genet. 1995 Sep;11(1):71-5.
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