Camk2a

Species Rattus norvegicus
Alternate Name(s) PKCCD, PK2CDD
Description calcium/calmodulin-dependent protein kinase II alpha subunit
Chromosome 18
Locus 18q11
Reference(s) Dong Y, Rosenberg HC. Brief seizure activity alters Ca2+/calmodulin dependent protein kinase II dephosphorylation and subcellular distribution in rat brain for several hours. Neurosci Lett. 2004 Mar 4;357(2):95-8.

Morimoto K, Sato K, Kashihara K, Hayabara T. Increased levels of mRNA for beta- but not alpha-subunit of calmodulin kinase II following kindled seizures. Brain Res Bull. 1997;43(4):375-80.

Murray KD, Gall CM, Benson DL, Jones EG, Isackson PJ. Decreased expression of the alpha subunit of Ca2+/ calmodulin-dependent protein kinase type II mRNA in the adult rat CNS following recurrent limbic seizures. Brain Res Mol Brain Res. 1995 Sep;32(2):221-32.

Singleton MW, Holbert WH, Lee AT, Bracey JM, Churn SB. Modulation of CaM Kinase II Activity Is Coincident with Induction of Status Epilepticus in the Rat Pilocarpine Model. Epilepsia. 2005 Sep;46(9):1389-400.

Singleton MW, Holbert WH 2nd, Ryan ML, Lee AT, Kurz JE, Churn SB. Age dependence of pilocarpine-induced status epilepticus and inhibition of CaM kinase II activity in the rat. Brain Res Dev Brain Res. 2005 Apr 21;156(1):67-77.

Yechikhov S, Morenkov E, Chulanova T, Godukhin O, Shchipakina T. Involvement of cAMP- and Ca(2+)/calmodulin-dependent neuronal protein phosphorylation in mechanisms underlying genetic predisposition to audiogenic seizures in rats. Epilepsy Res. 2001 Jul;46(1):15-25.

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