| Species |
Mus musculus |
| Alternate Name(s) |
hamartin |
| Description |
tuberous sclerosis 1
|
| Chromosome |
2
|
| Locus |
2 A3 |
| Human Homolog |
TSC1
|
| Protein Alignment |
Homo sapiens:
Mus musculus:
 |
| Reference(s) |
Meikle L, Talos DM, Onda H, Pollizzi K, Rotenberg A, Sahin M, Jensen FE, Kwiatkowski DJ. A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival. J Neurosci. 2007 May 23;27(21):5546-58.
Floricel F, Higaki K, Maki H, Nanba E, Ninomiya H, Ohno K. Antisense suppression of TSC1 gene product, hamartin, enhances neurite outgrowth in NGF-treated PC12h cells. Brain Dev. 2007 Mar 19; 29(8):502-9. Epub 2007 Mar 21.
Uhlmann EJ, Wong M, Baldwin RL, Bajenaru ML, Onda H, Kwiatkowski DJ, Yamada K, Gutmann DH. Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures. Ann Neurol. 2002 Sep;52(3):285-96.
Wong M, Ess KC, Uhlmann EJ, Jansen LA, Li W, Crino PB, Mennerick S, Yamada KA, Gutmann DH. Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model. Ann Neurol. 2003 Aug;54(2):251-6.
|
