unc-104

Species Caenorhabditis elegans
Alternate Name(s) C52E12.2, klp-1
Description kinesin-like protein, monomeric synaptic vesicle transport motor, UNCoordinated locomotion
Chromosome II
Locus II +0.15 cM
Video unc-104 on 10 mg/mL PTZ
Reference(s) Hall DH, Hedgecock EM. Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans. Cell. 1991 May 31;65(5):837-47.

Koushika SP, Schaefer AM, Vincent R, Willis JH, Bowerman B, Nonet ML. Mutations in Caenorhabditis elegans cytoplasmic dynein components reveal specificity of neuronal retrograde cargo. J Neurosci. 2004 Apr 21;24(16):3907-16.

Otsuka AJ, Jeyaprakash A, Garcia-Anoveros J, Tang LZ, Fisk G, Hartshorne T, Franco R, Born T. The C. elegans unc-104 gene encodes a putative kinesin heavy chain-like protein. Neuron. 1991 Jan;6(1):113-22.

Williams SN, Locke CJ, Braden AL, Caldwell KA, Caldwell GA. Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in C. elegans. Hum Mol Genet. 2004 Sep 15;13(18):2043-59. Epub 2004 Jul 14.

[Entrez Cross-Database Search] [Entrez Gene] [Pfam] [Swiss-Prot] [UniProt]