unc-49

Species Caenorhabditis elegans
Alternate Name(s) T21C12.1
Description ionotropic GABA receptor subunit
Chromosome III
Locus III +3.01 cM
Human Homolog GABRA1
Mouse Homolog Gabra1
Protein Alignment Homo sapiens:

Caenorhabditis elegans:
Video unc-49 on 10 mg/mL PTZ
Reference(s) Bamber BA, Beg AA, Twyman RE, Jorgensen EM. The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor. J Neurosci. 1999 Jul 1;19(13):5348-59.

Bamber BA, Richmond JE, Otto JF, Jorgensen EM. The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction. Br J Pharmacol. 2005 Feb;144(4):502-9.

Bamber BA, Twyman RE, Jorgensen EM. Pharmacological characterization of the homomeric and heteromeric UNC-49 GABA receptors in C. elegans. Br J Pharmacol. 2003 Mar;138(5):883-93.

Cinar H, Keles S, Jin Y. Expression profiling of GABAergic motor neurons in Caenorhabditis elegans. Curr Biol. 2005 Feb 22;15(4):340-6.

McIntire SL, Jorgensen E, Horvitz HR. Genes required for GABA function in Caenorhabditis elegans. Nature. 1993 Jul 22;364(6435):334-7.

Williams SN, Locke CJ, Braden AL, Caldwell KA, Caldwell GA. Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in C. elegans. Hum Mol Genet. 2004 Sep 15;13(18):2043-59. Epub 2004 Jul 14.

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