Author
Chromosome
Description
Gene
Keyword
Species
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unc-49
Species
Caenorhabditis elegans
Alternate Name(s)
T21C12.1
Description
ionotropic GABA receptor subunit
Chromosome
III
Locus
III +3.01 cM
Human Homolog
GABRA1
Mouse Homolog
Gabra1
Protein Alignment
Homo sapiens:
Caenorhabditis elegans:
Video
unc-49 on 10 mg/mL PTZ
Reference(s)
Bamber BA, Beg AA, Twyman RE, Jorgensen EM.
The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor
. J Neurosci. 1999 Jul 1;19(13):5348-59.
Bamber BA, Richmond JE, Otto JF, Jorgensen EM.
The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction
. Br J Pharmacol. 2005 Feb;144(4):502-9.
Bamber BA, Twyman RE, Jorgensen EM.
Pharmacological characterization of the homomeric and heteromeric UNC-49 GABA receptors in C. elegans
. Br J Pharmacol. 2003 Mar;138(5):883-93.
Cinar H, Keles S, Jin Y.
Expression profiling of GABAergic motor neurons in Caenorhabditis elegans
. Curr Biol. 2005 Feb 22;15(4):340-6.
McIntire SL, Jorgensen E, Horvitz HR.
Genes required for GABA function in Caenorhabditis elegans
. Nature. 1993 Jul 22;364(6435):334-7.
Williams SN, Locke CJ, Braden AL, Caldwell KA, Caldwell GA. Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in C. elegans. Hum Mol Genet. 2004 Sep 15;13(18):2043-59. Epub 2004 Jul 14.
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