unc-25

Species Caenorhabditis elegans
Alternate Name(s) Y37D8A.23
Description glutamic acid decarboxylase
Chromosome III
Locus III +19.50 cM
Human Homolog GAD1
Rat Homolog Gad1
Protein Alignment Homo sapiens:

Caenorhabditis elegans:
Reference(s) Cinar H, Keles S, Jin Y. Expression profiling of GABAergic motor neurons in Caenorhabditis elegans. Curr Biol. 2005 Feb 22;15(4):340-6.

Locke CJ, Williams SN, Schwarz EM, Caldwell GA, Caldwell KA. Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans. Brain Res. 2006 Sep 20; [Epub ahead of print]

McIntire SL, Jorgensen E, Horvitz HR. Genes required for GABA function in Caenorhabditis elegans. Nature. 1993 Jul 22;364(6435):334-7.

Williams SN, Locke CJ, Braden AL, Caldwell KA, Caldwell GA. Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in C. elegans. Hum Mol Genet. 2004 Sep 15;13(18):2043-59. Epub 2004 Jul 14.

[Entrez Cross-Database Search] [Entrez Gene] [Pfam] [Swiss-Prot] [UniProt]