Bdnf

Species Rattus norvegicus
Description brain derived neurotrophic factor
Chromosome 3
Locus 3q33
Human Homolog BDNF
Mouse Homolog Bdnf
Protein Alignment Homo sapiens:

Rattus norvegicus:
Reference(s) Altar CA, Laeng P, Jurata LW, Brockman JA, Lemire A, Bullard J, Bukhman YV, Young TA, Charles V, Palfreyman MG. Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways. J Neurosci 2004 24:2667-2677.

Altar CA, Whitehead RE, Chen R, Wortwein G, Madsen TM. Effects of electroconvulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain. Biol Psychiatry (2003) 54:703-709.

Binder DK, Routbort MJ, McNamara JO. Immunohistochemical evidence of seizure-induced activation of trk receptors in the mossy fiber pathway of adult rat hippocampus. J Neurosci. 1999 Jun 1;19(11):4616-26.

Foster JA, Puchowicz MJ, McIntyre DC, Herkenham M. Activin mRNA induced during amygdala kindling shows a spatiotemporal progression that tracks the spread of seizures. J Comp Neurol. 2004 Aug 9;476(1):91-102.

Jacobsen JP, Mork A. The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. Brain Res. 2004 Oct 22;1024(1-2):183-92.

Reibel S, Larmet Y, Carnahan J, Marescaux C, Depaulis A. Endogenous control of hippocampal epileptogenesis: a molecular cascade involving brain-derived neurotrophic factor and neuropeptide Y. Epilepsia. 2000;41 Suppl 6:S127-33.

Rivera C, Li H, Thomas-Crusells J, Lahtinen H, Viitanen T, Nanobashvili A, Kokaia Z, Airaksinen MS, Voipio J, Kaila K, Saarma M. BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion. J Cell Biol. 2002 Dec 9;159(5):747-52. Epub 2002 Dec 09.

Scharfman HE, Goodman JH, Sollas AL. Actions of brain-derived neurotrophic factor in slices from rats with spontaneous seizures and mossy fiber sprouting in the dentate gyrus. J Neurosci. 1999 Jul 1;19(13):5619-31.

Tsankova NM, Kumar A, Nestler EJ. Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J Neurosci. 2004 Jun 16;24(24):5603-10.

Xu B, Michalski B, Racine RJ, Fahnestock M. The effects of brain-derived neurotrophic factor (BDNF) administration on kindling induction, Trk expression and seizure-related morphological changes. Neuroscience. 2004;126(3):521-31.

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