| Species | Caenorhabditis elegans |
| Alternate Name(s) | T03F6.5, pnm-1 |
| Description | human LISsencephaly gene related |
| Chromosome | III |
| Locus | III +20.87 cM |
| Human Homolog | LIS1 |
| Mouse Homolog | Lis1 |
| Protein Alignment | Homo sapiens:
Caenorhabditis elegans:  |
| Video | lis-1 homozygote on 10 mg/mL PTZ |
| Reference(s) |
Dawe AL, Caldwell KA, Harris PM, Morris NR, Caldwell GA. Evolutionarily conserved nuclear migration genes required for early embryonic development in Caenorhabditis elegans. Dev Genes Evol. 2001 Sep;211(8-9):434-41.
Locke CJ, Williams SN, Schwarz EM, Caldwell GA, Caldwell KA. Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans. Brain Res. 2006 Sep 20; [Epub ahead of print] Williams SN, Locke CJ, Braden AL, Caldwell KA, Caldwell GA. Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in C. elegans. Hum Mol Genet. 2004 Sep 15;13(18):2043-59. Epub 2004 Jul 14. |